For US residents only.
KYMRIAH™ (tisagenlecleucel) is not a pill, chemotherapy, or transplant. KYMRIAH is a type of cutting-edge immunocellular therapy that uses the power of your own immune system to treat your cancer.
Watch this brief video to learn how KYMRIAH works.
A natural defender, the T cell is a part of your immune system. T cells detect and destroy infected or cancerous cells by looking for certain antigens. Antigens are markers on cells that help your immune system identify normal cells from infected or cancerous cells; however, your cancerous B cells look like normal B cells.
After KYMRIAH, your T cells will be able to recognize an antigen on your B cells called CD19. By reprogramming your T cells, KYMRIAH enhances their ability to detect and destroy your B cells, including those with cancer in them. Because KYMRIAH uses your own T cells, you may hear it referred to as an “individualized” therapy made just for you. After being treated with KYMRIAH, you may not need any other treatment for your cancer.
To learn more about the therapy process with KYMRIAH, go to What is the process for getting KYMRIAH?.
To learn more about KYMRIAH, download Your guide to KYMRIAH therapy.
KYMRIAH is approved to treat children and young adults whose B-cell ALL is refractory or in second or later relapse. KYMRIAH is a therapy option for those looking for a different way to try to treat their cancer because previous treatments have not kept their cancer in remission. If you are considering treatment options, ask your doctor about KYMRIAH.
Topics to discuss with your doctor:
KYMRIAH is a unique therapy that starts and ends with you. Your cells make KYMRIAH possible, so the process begins with your T cell collection and ends with infusing them back into you. For a more detailed description of KYMRIAH therapy, go to What is the KYMRIAH therapy process?
KYMRIAH is different from other cancer therapies because it is a treatment that comes from within you.